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среда, 21 декабря 2011 г.

Some new drugs will soon replace anabolic steroids

Scientists intend to find alternative drugs to anabolic steroids and other performance-enhancing drugs. They claim that sportsmen may soon have another way to increase muscles. The Salk Institute has pointed out that the efforts of the specialists have got success. Recent studies have displayed that inactivation of a genome regulator which is known as “NCoR1” leads to increase of muscle size, strength and endurance. The leader of the researches conducted in the Salk Institute, Ronald Evans, confirms that this knowledge can lead to development of several new medicines that will benefit not only for athletes and bodybuilders that train but also for people that are sedentary.
The specialists of the Salk Institute notice about people who can’t do physical exercises because they have got different health troubles, such as diabetes, frailty, immobility and other physical or psychological aspects that cause sedentarism. The specialists intend to develop some specific medicines which could benefit for sedentary persons so, as exercises benefit for healthy individuals. Now they experiment with sedentary mice.
As for anabolic steroids, they may cause some muscle-building effects in sedentary people. But people that administrate anabolic steroids should train and alter their diets to reach more significant results.
If new preparations which suppress NCoR1 are developed by scientists successfully, they will cause essential changes in sedentary individuals. But could you imagine which positive effects will be caused in athletes?
But there is also an essential difference between anabolic steroids and NCoR1 suppression. It is known that anabolic steroids lead to unwanted results; some of them may be quite dangerous for health and even life-threatening. Moreover, anabolic steroids can cause serious undesirable effects especially in females. But as for NCoR1 suppression, specialists assure that drugs which will suppress this genome regulator will not cause side reactions.
There is an article about NCoR1 suppression which has got the following title: “NCoR1 Is a Conserved Physiological Modulator of Muscle Mass and Oxidative Function”. It represents results of different experiments that enrolled mice and nematodes. The experiments have displayed that NCoR1 suppression benefits for muscle size very much. The mice with suppression of this genome regulator had more increased muscles and ran faster than others.
Unfortunately, the mice with NCoR1 suppression were not compared with the mice that were given anabolic steroids. If these two types of mice were compared, the results of the experiments would be very valuable for further researches and conclusions.
It is possible to mention that elder individuals and people who suffer of muscle dystrophy will be soon involved in studies to find out positive effects of new potential medicines.

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